Products CartiGen HP: Hydrostatic Pressure Bioreactor Systems

As regenerative medicine carves out the future of health care, it has become critical to investigate and understand the relationship between cells and their environment. New tissue engineered products cannot be developed in a commercial setting without a solid foundation of how these cells behave in their native tissue.

BISS's CartiGen HP is a hydrostatic pressure bioreactor that is applicable to any dimension and mechanical integrity of cell-seeded construct. The bioreactor holds multiple formats of tissue culture plastics and enable high throughput of samples for analyzing simultaneously to facilitate the screening studies for the three classes of scaffold materials and cell isolates as well as human femur. The bioreactor generates a variable hydrostatic pressure and long term intermittent cyclical hydrostatic forces in a standard incubator accommodating both monolayer and 3D culture scaffolds at frequencies of 0.3 Hz and 1 HZ.

The CartiGen HP bioreactor system includes a pressurization system and servo manifold. Incubator air is first pressurized then routed to the manifold where the pressure is modulated before being routed to the chamber(s). Using this approach, pressures up to 45 psi per chamber can be created. The system provides heating and hydration of the air to mitigate changes in the chamber media temperature and humidity.

Chamber Dimensions:
14"(380mm);L x 10"(254mm);W x 8.5"(216mm);H       Weight: 11.5lbs (5.2kg)

 

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